#  Saturated Reconstruction of a Volume of Neocortex 

 



 [](/file_url/133)

   ![video_cover_lichtman_cell_2015.png](/sites/g/files/omnuum7466/files/styles/hwp_1_1__720x720_scale/public/lichtman/files/video_cover_lichtman_cell_2015_0.png?itok=DKLE0m60) 

 

 **Read the original research article in Cell:**

 [Saturated Reconstruction of a Volume of Neocortex.](http://www.ncbi.nlm.nih.gov/pubmed/26232230) Kasthuri N, Hayworth KJ, Berger DR, Schalek RL, Conchello JA, Knowles-Barley S, Lee D, Vázquez-Reina A, Kaynig V, Jones TR, Roberts M, Morgan JL, Tapia JC, Seung HS, Roncal WG, Vogelstein JT, Burns R, Sussman DL, Priebe CE, Pfister H, Lichtman JW. *Cell*. 2015 Jul 30;162(3):648-61. \[[with Video Abstract](/file_url/133)\]

 Read Jeff Lichtman’s [summary of the study](https://www.mcb.harvard.edu/mcb/news/news-detail/3821/reconstructing-the-brains-wiring-diagram-lichtman-lab/) on the Harvard Molecular and Cellular Biology website.

 Read the Conte Center web feature, ["Imaging the Brain's Jungles: A Miniscule Yet Monumental Leap Forward"](http://www.conte.harvard.edu/news/2015/8/18/imaging-the-brains-jungles-a-miniscule-yet-monumental-leap-forward)

 **Additional Resources:**

 [Connectomics: Big Microscopes & Tiny Synapses](https://vimeo.com/87951765). A video made for Harvard’s “Fundamentals of Neuroscience,” course, featuring Jeff Lichtman and Bobby Kasthuri.

 [Crumb of mouse brain reconstructed in full detail](http://www.nature.com/news/crumb-of-mouse-brain-reconstructed-in-full-detail-1.18105): Digital map is step towards reconstructing a whole human brain. Nature news article by Alison Abbott, with video. July 30, 2015.

 [From tiny slice, researchers lay bare beauty of mouse brain](http://sfari.org/news-and-opinion/news/2015/from-tiny-slice-researchers-lay-bare-beauty-of-mouse-brain?utm_source=Autism%20research%20news%20from%20SFARI.org&utm_campaign=6fdf36932a-SFARI_Newsletter_20150804&utm_medium=email&utm_term=0_0a60ccb345-6fdf36932a-388510201). Simons Foundation Autism Research Initiative (SFARI) news story by Jessica Wright. July 30, 2015.

 [3D brain map reveals connections between cells in nano-scale](http://www.theguardian.com/science/2015/jul/30/3d-brain-map-reveals-connections-between-cells-in-nano-scale). The Guardian news piece by Helen Thomson. July 30, 2015.

 [These Stunning Images Will Take You On A Journey Through The Brain](http://www.huffingtonpost.com/entry/mouse-brain-color-images_55bf7abbe4b0b23e3ce33ef2). Huffington Post story by Carolyn Gregoire. August 4, 2015.

 [BRAIN Investigators Produce Automated Technique Allowing High Resolution Reconstruction of Mouse Cortex](http://www.brainupdate.nih.gov/brain-investigators-produce-automated-technique-allowing-high-resolution-reconstruction-of-mouse-cortex/). NIH BRAIN Initiative website. August 11, 2015.

 [Your brain is more complicated than you can imagine](https://www.facebook.com/ScienceNOW/videos/vl.1456158701348095/10153054041815108/?type=1&theater). ScienceNow video on Facebook. August 8, 2015.